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The most commonly reported symptoms accompanying acute and chronic overdoses of STRATTERA were gastrointestinal symptoms, somnolence, dizziness, tremor, and abnormal behavior.

Hyperactivity and agitation have also been reported. Signs and symptoms consistent Strattera 10 mg Generique site Fiable mild to moderate sympathetic nervous system activation e. Most events were mild to moderate. Because atomoxetine is highly protein-bound, dialysis is not likely to be useful in the treatment of overdose. Some cases presented with features resembling neuroleptic malignant syndrome.

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Pheochromocytoma Serious reactions, including elevated blood pressure and tachyarrhythmia, have been reported in patients with pheochromocytoma or a Strattera 10 mg Generique site Fiable of mascotas30.proyects10.es increases in blood pressure or heart rate that could be clinically important for example, 15 to 20 mm Hg in blood pressure or 20 beats per minute in heart rate. Pharmacodynamics An exposure-response analysis encompassing doses of atomoxetine 0.

The exposure-efficacy relationship was similar to that observed between dose and efficacy with median Marque De Motilium 10 mg at the two highest doses resulting in near maximal changes from baseline. No large changes in QTc interval i, Strattera 10 mg Generique Site Fiable. However, small changes in QTc interval cannot be excluded from the current study, because the study failed to demonstrate assay sensitivity. There was a slight increase in QTc interval with increased atomoxetine Strattera 10 mg Generique site Fiable.

It is eliminated primarily by oxidative metabolism through the cytochrome P450 2D6 CYP2D6 enzymatic pathway and subsequent glucuronidation. Atomoxetine has a half-life of about 5 hours. These individuals have reduced activity in this pathway resulting in 10-fold higher AUCs, 5-fold higher peak plasma concentrations, and slower elimination plasma half-life of about 24 hours of atomoxetine compared with people with normal activity.

The pharmacokinetics of atomoxetine have been evaluated in more than 400 children and adolescents in selected clinical trials, primarily using population pharmacokinetic studies. Single-dose and steady-state individual pharmacokinetic data were also obtained in children, adolescents, and adults. Clearance and volume of distribution after adjustment for body weight were also similar. Maximal plasma concentrations Cmax are reached approximately 1 to 2 hours after dosing. Volume of distribution is similar across the patient weight range after normalizing for body weight. People with reduced activity in this pathway PMs have higher plasma concentrations of atomoxetine compared with people with normal activity EMs.

Atomoxetine did not inhibit or induce the CYP2D6 pathway. The major oxidative Strattera 10 mg Generique site Fiable formed, regardless of CYP2D6 status, is 4-hydroxyatomoxetine, which is glucuronidated. Strattera may also be used for purposes not listed in this medication guide. Important information You should not use Strattera if you have narrow-angle glaucoma, an adrenal gland tumor, heart disease or coronary artery disease, or moderate to severe high blood pressure.

Do not use Strattera if you have taken a MAO inhibitor in the past 14 days, including isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. Strattera may cause new or worsening psychosis unusual thoughts or behavior, especially if you have a history of depression, mental illness, or bipolar disorder. Strattera has caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect.

Some young people have thoughts about suicide when they first start taking this medicine, or whenever the dose is changed. Stay alert to changes in your mood or symptoms, especially if you have ever had suicidal Strattera 10 mg Generique sites Fiable. Before taking this medicine Do not use Strattera if you have used an MAO inhibitor in the past 14 days. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. You should not use this medicine if you are allergic to atomoxetine, or if you have: Strattera has caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have: To make sure this medicine is safe for you, tell your doctor if you or anyone in your Strattera 10 mg Generique site Fiable has ever had: Some young people have thoughts about suicide when first taking Strattera, or whenever the dose is changed.

Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

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It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant before taking Strattera.

  • Tell your doctor if you are breast-feeding a baby.
  • Patients should be given the opportunity to discuss the contents of the Medication Guide and to obtain answers to any questions they may have.
  • These findings were observed at doses that caused slight maternal toxicity.
  • Avoid using or handling an open or broken capsule.

It is not known whether atomoxetine passes into breast milk or if it could affect a nursing baby. Tell your doctor if you are breast-feeding a baby while taking Strattera.

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Strattera is not FDA-approved for use by anyone younger than 6 years old. How should I take Strattera? To make buy Cipro this Strattera 10 mg Generique site Fiable is safe for Strattera 10 mg Generique site Fiable, tell your doctor if you or anyone in your family has ever had: Some young people have thoughts about suicide when first taking atomoxetine, or whenever the dose is changed. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. It is not known whether this medicine will harm an unborn baby.

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Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether atomoxetine Strattera 10 mg Generique sites Fiable into breast milk or if it could affect a nursing baby. Tell your doctor if you are breast-feeding a baby. Atomoxetine is not approved for use by anyone younger than 6 years old. How should I take atomoxetine Strattera?

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